HORDB

General Information

ID: hor000902
Uniprot ID: NA
Protein name: Cholecystokinin 8
Gene name: NA
Organism: Calliphora vomitoria
Family: Gastrin/cholecystokinin family
Source: animal
Expression: the brain and thoracic ganglion
Disease: NA
Comments: NA
Taxonomy: NA
GO MF: NA
GO BP: NA
GO CC: NA

Sequence Information

Sequence: DYMGWMDF
Length: 8
Propeptide: NA
Signal peptide: NA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Activity

Function: NA
Mechanism: NA
Cross BBB: YES
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: 18 minute; /1080 seconds ( PubMed ID: 6291099 )

Structure

Disulfide bond: NA
Structure ID: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000902_AF2.pdb

hor000902_ESM.pdb

Physical Information

Mass:	118924	Formula:	C49H61N9O14S2
Absent amino acids:	ACEHIKLNPQRSTV	Common amino acids:	DM
pI:	3.49	Basic residues:	0
Polar residues:	2	Hydrophobic residues:	2
Hydrophobicity:	-37.5	Boman Index:	-663
Half-Life:	1.1 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	0
Instability Index:	9927.5	Extinction Coefficient cystines:	6990
Absorbance 280nm:	998.57

Literature

PubMed ID: 8118842##6291099
Title: Localisation of Sulfakinin Neuronal Pathways in the Blowfly Calliphora Vomitoria